Isochlorogenic acid A
CAS No. : 2450-53-5
(Synonyms: 3,5-Dicaffeoylquinic acid; 3,5-CQA)
| Size | Price | Stock |
|---|---|---|
| 5mg | $74 | In-stock |
| 10mg | $115 | In-stock |
| 25mg | $240 | In-stock |
| 50mg | $380 | In-stock |
| 100mg | $580 | In-stock |
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| Cat. No. : | HY-N0056 |
| M.Wt: | 516.45 |
| Formula: | C25H24O12 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 50 mg/mL |
Isochlorogenic acid A (3,5-Dicaffeoylquinic acid) is a natural phenolic acid with anti-mutagenicity, anti-HBV, anti-HIV, anti-oxidant, anti-bacterial, and anti-inflammatoryy activities[1].
In Vitro:Isochlorogenic acid A inhibits the aminoacylation activity of LeuRS from Giardia lamblia (GlLeuRS), with an IC50 of 5.82 μg/mL[1].
Isochlorogenic acid A (5-100 μM, 48 h) increases melanin content in B16 cells, and increases TYR proteins activity[4].
Isochlorogenic acid A shows DPPH (IC50=4.26 µg/mL), ABTS radical scavenging activity[6].
Isochlorogenic acid A (0-250 μg/mL, 24 h) inhibits nitric oxide production in LPS-stimulated RAW 264.7 cells[6].
In Vivo:Isochlorogenic acid A (5 and 10 mg/kg, p.o., once a day for 3 weeks) ameliorates cognitive impairment induced by TMT in ICR male mice[5].
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