Eicosanedioic acid
CAS No. : 2424-92-2
| Size | Price | Stock |
|---|---|---|
| 1g | $10 | In-stock |
| 5g | $31 | In-stock |
| 25g | $112 | In-stock |
| 100g | $375 | In-stock |
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| 500 g | Get quote | |
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| Cat. No. : | HY-W034595 |
| M.Wt: | 342.51 |
| Formula: | C20H38O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic) |
Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
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