Catalpol
CAS No. : 2415-24-9
(Synonyms: Catalpinoside)
| Size | Price | Stock |
|---|---|---|
| 25mg | $40 | In-stock |
| 50mg | $70 | In-stock |
| 100mg | $110 | In-stock |
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| Cat. No. : | HY-N0820 |
| M.Wt: | 362.33 |
| Formula: | C15H22O10 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 30 mg/mL;H2O : 7.14 mg/mL (ultrasonic;warming;heat to 60°C) |
Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects[1][2][3]. In Vitro: Catalpol (0.1 μg/mL; for 3 days) can induce neuronal differentiation in PC12 cells through activation of the intracellular signal transduction pathway, and promote neurite length[2]. In Vivo: Catalpol (25-100 mg/kg; intraperitoneal injection; once) treatment clearly reduces blood urea nitrogen, serum creatinine levels and the expression of KIM-1 in renal ischemia/reperfusion-injury (IRI) mice. Catalpol markedly reduces the expression of PI3K, Akt and eNOS levels, and suppresses the TNF-α, IL-1β, IL-6 and IL-10 activities[1].
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