NSC689857


CAS No. : 241127-79-7

241127-79-7
Price and Availability of CAS No. : 241127-79-7
Size Price Stock
5mg $220 In-stock
10mg $350 In-stock
25mg $700 In-stock
50mg $1120 In-stock
100mg $1790 In-stock
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Cat. No. : HY-123578
M.Wt: 407.50
Formula: C25H29NO4
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 241127-79-7 :

NSC689857 is a potent EGFR and SCFSKP2 inhibitor with an IC50 value of 36 μM for Skp2-Cks1. NSC689857 can inhibit p27 ubiquitylation (IC50=30 μM). NSC689857 has varied activity across cancer types, with more activity against leukemia cell lines than others[1][2]. IC50 & Target: IC50: 36 μM (Skp2-Cks1), 30 μM (p27 ubiquitylation)[1]

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