l-Naproxen


CAS No. : 23979-41-1

(Synonyms: (R)-Naproxen)

23979-41-1
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Cat. No. : HY-15031
M.Wt: 230.26
Formula: C14H14O3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 23979-41-1 :

l-Naproxen ((R)-Naproxen) is an enantiomer of (S)-Naproxen. l-Naproxen can inhibit Cdc42 and Rac1 (EC50=96 μM and 212 μM, respectively), and show anti-tumor activity. l-Naproxen is a nonsteroidal antiinflammatory agent (NSAID)[1][2][3]. In Vitro: l-Naproxen (30-1000 μM; 2 h) inhibits Rac1 and Cdc42 activity selectively in HeLa cells[3].
l-Naproxen (0-300 μM; 48 h) inhibits migration of immortalized human ovarian cancer cells[3].
l-Naproxen (300 μM; 48 h) shows activity via a COX-independent mechanism[3].

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