Cinepazide


CAS No. : 23887-46-9

23887-46-9
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Cat. No. : HY-66010A
M.Wt: 417.50
Formula: C22H31N3O5
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 23887-46-9 :

Cinepazide is a piperazine derivative and acts as a weak calcium channel blocker. Cinepazide is a potent vasodilator and can be used for the research of cerebrovascular diseases, including ischemic stroke, brain?infarct et. al[1]. In Vivo: Cinepazide (intravenous?injection; 30 mg/kg) potentiates the vertebral vasodilator response of dogs to intravertebral adenosine and cyclic AMP, while cinnarizine reduces their vasodilator effects[1].
Cinepazide (intravertebral injection; 1-10 mg/kg) increases vertebral blood flow in a dose-related manner and the effect is partially inhibited by Aminophylline (HY-B0140)?in dogs[1].

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