Ambroxol (hydrochloride)
CAS No. : 23828-92-4
(Synonyms: NA-872 (hydrochloride))
| Size | Price | Stock |
|---|---|---|
| 25g | $62 | In-stock |
| 100g | $186 | In-stock |
| 500g | $558 | In-stock |
| 1000g | $948 | In-stock |
| > 2 kg | Get quote | |
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| Cat. No. : | HY-B1039A |
| M.Wt: | 414.56 |
| Formula: | C13H19Br2ClN2O |
| Purity: | >98 % |
| Solubility: | H2O : 8.33 mg/mL (ultrasonic) |
Ambroxol hydrochloride (NA-872 hydrochloride), an active metabolite of the prodrug Bromhexine, has potent expectorant effects. Ambroxol hydrochloride is a glucocerebrosidase (GCase) chaperone and increases glucocerebrosidase activity. Ambroxol hydrochloride induces lung autophagy and has the potential for Parkinson disease and neuronopathic Gaucher disease research[1][2]. In Vivo: Ambroxol hydrochloride (NA-872 hydrochloride; 1, 3, 4, 5 mM for 12 consecutive days in drinking water) results in increased brain glucocerebrosidase activity in wild-type mice, transgenic mice expressing the heterozygous L444P mutation in the murine glucocerebrosidase 1 gene, and transgenic mice overexpressing human α-synuclein[2].
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