3-Methylthiophene-2-carboxylic acid
CAS No. : 23806-24-8
| Size | Price | Stock |
|---|---|---|
| 10g | $13 | In-stock |
| 25g | $17 | In-stock |
| 100g | $66 | In-stock |
| 500g | $323 | In-stock |
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| Cat. No. : | HY-W004782 |
| M.Wt: | 142.18 |
| Formula: | C6H6O2S |
| Purity: | >98 % |
| Solubility: |
3-Methylthiophene-2-carboxylic acid (compound 3) is a potent Pseudomonas quinolone signal system protein E (PqsE) inhibitor with a Kd of 19.6 µM and an IC50 of 40 µM. 3-Methylthiophene-2-carboxylic acid binds to the active center of PqsE and shows inhibition of the thioesterase activity. Methylthiophene-2-carboxylic acid can permeate into P. aeruginosa and affect 2,4-dihydroxyquinoline (DHQ) levels to a similar extent as deletion of the PqsE gene. 3-Methylthiophene-2-carboxylic acid can be used for cystic fibrosis research[1].
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