Nardosinone
CAS No. : 23720-80-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $60 | In-stock |
| 10mg | $90 | In-stock |
| 20mg | $140 | In-stock |
| 50mg | $260 | In-stock |
| 100mg | $380 | In-stock |
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| Cat. No. : | HY-N0380 |
| M.Wt: | 250.33 |
| Formula: | C15H22O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Nardosinone, isolated from Nardostachys chinensis, is the first enhancer of the neuritogenic action of dbcAMP and staurosporine. Nardosinone may become a useful pharmacological tool for studying the mechanism of action of not only nerve growth factor (NGF) but also both the neuritogenic substances[1]. In Vitro: Nardosinone (0.1-100 microM) enhanced dibutyryl cyclic AMP (dbcAMP, 0.3 mM)- and staurosporine (10 nM)-induced neurite outgrowth from PC12D cells in a concentration-dependent manner. Nardosinone enhances a downstream step of MAP kinase in the MAP kinase-dependent signaling pathway[1].
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