N,N-Bis(3-aminopropyl)dodecylamine

N,N-Bis(3-aminopropyl)dodecylamine is a potent fungicidal agent with remarkable activity against Aspergillus niger. N,N-Bis(3-aminopropyl)dodecylamine induces oxidative stress and regulates the activities of multiple antioxidant and mitochondrial enzymes in a concentration‑ and duration‑dependent manner. N,N-Bis(3-aminopropyl)dodecylamine disrupts fungal organelles, remodels mitochondrial morphology and impairs mitochondria‑related cellular functions. N,N-Bis(3-aminopropyl)dodecylamine can be used for the research of fungicidal mechanisms and oxidative stress in Aspergillus niger^[1]. In Vitro:N,N-Bis(3-aminopropyl)dodecylamine (apd) (0.05-0.1%, v/v; 1-24 h) modulates antioxidant and mitochondrial enzyme activities in Aspergillus niger mycelium in a concentration‑ and time‑dependent manner. It markedly increases total SOD, CAT, GSP, SDG and NDG activities at 4 h, and restores FHT activity after an initial reduction, with CAT activity peaking at 344% of the control^[1].