tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate


CAS No. : 236406-55-6

236406-55-6
Price and Availability of CAS No. : 236406-55-6
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Cat. No. : HY-30756
M.Wt: 226.32
Formula: C12H22N2O2
Purity: >98 %
Solubility:
Introduction of 236406-55-6 :

tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate is a PROTAC linker. tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate can be used in the synthesis of PROTAC ER Degrader-12 (HY-160264) and PROTAC AR Degrader-9 (HY-170332)[1]. In Vitro:PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

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