Kaempferol 3-O-β-D-galactopyranoside


CAS No. : 23627-87-4

(Synonyms: Trifolin)

23627-87-4
Price and Availability of CAS No. : 23627-87-4
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10mg $550 In-stock
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Cat. No. : HY-N6605
M.Wt: 448.38
Formula: C21H20O11
Purity: >98 %
Solubility: DMSO : 25 mg/mL (ultrasonic)
Introduction of 23627-87-4 :

Kaempferol 3-O-β-D-galactopyranoside (Trifolin) is an orally active flavonoid derivative that can be found in the aerial parts of Consolida oliverana. Kaempferol 3-O-β-D-galactopyranoside exhibits antitumor and cardioprotective effects[1][2][3]. In Vitro:Kaempferol 3-O-β-D-galactopyranoside (12.5–50 μM, 24-48 h) inhibits the proliferation of NCI-H460 cells in a dose-dependent manner[2].
Kaempferol 3-O-β-D-galactopyranoside (12.5–50 μM, 48 h) increases the Sub-G1 phase cell population and induces apoptosis in NCI-H460 cells[2].
Kaempferol 3-O-β-D-galactopyranoside (12.5–50 μM, 48 h) modulates intrinsic and extrinsic apoptosis signaling pathways and induces apoptosis in NCI-H460 cells[2].
In Vivo:Kaempferol 3-O-β-D-galactopyranoside (0.1–10.0 mg/kg, p.o., once daily for 4 weeks) improves cardiac function and reduces cardiomyocyte apoptosis in Angiotensin II (AngII) (HY-13948)-induced hypertensive cardiac injury C57BL/6 mice model[3].

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