Thiophanate-Methyl
CAS No. : 23564-05-8
| Size | Price | Stock |
|---|---|---|
| 500mg | $40 | In-stock |
| 1g | $65 | In-stock |
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| Cat. No. : | HY-B0842 |
| M.Wt: | 342.39 |
| Formula: | C12H14N4O4S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 200 mg/mL (ultrasonic) |
Thiophanate-Methyl is a pesticide residue and fungicide. Thiophanate-Methyl induces hepatotoxicity via caspase-3-mediated apoptosis and oxidative stress, thereby causing metabolic imbalance in the liver of zebrafish. Thiophanate-Methyl impairs the rhizobacteria-mediated defense response of cucumber against fusarium wilt[1][2][3][4].
In Vivo:Thiophanate-methyl (6.25-25 mg/L; water exposure; daily solution changes; 72 hours) induces severe, concentration-dependent hepatotoxicity in Danio rerio larvae via activation of caspase-3-mediated apoptosis and oxidative stress, leading to disrupted glucose and lipid metabolism, with no observed toxicity to other organs[1].
Thiophanate-methyl (2-6 mg/L; water exposure; daily 75% solution changes; 28 days) induces severe, concentration-dependent hepatotoxicity in adult Danio rerio, leading to disrupted glucose and lipid metabolism, with dose-specific alterations to liver glycogen content[1].
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