SIRT6-IN-6
CAS No. : 23491-48-7
| Size | Price | Stock |
|---|---|---|
| 5g | $27 | In-stock |
| 10g | $54 | In-stock |
| 25g | $131 | In-stock |
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| Cat. No. : | HY-16605 |
| M.Wt: | 236.28 |
| Formula: | C11H16N4O2 |
| Purity: | >98 % |
| Solubility: |
SIRT6-IN-6 (compound 6d) is a potent and selective SIRT6 inhibitor with an IC50 of 4.93 μM and a Ki of ~10 μM. SIRT6-IN-6 shows selectivity against other members of the HDAC family (SIRT1-3 and HDAC1-11). SIRT6-IN-6 significantly increases the level of glucose transporter GLUT-1, thereby reducing blood glucose in a mouse model of type 2 diabetes. SIRT6-IN-6 can be used for type 2 diabetes research[1].
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