ALE-0540
CAS No. : 234779-34-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $170 | In-stock |
| 10mg | $270 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-124637 |
| M.Wt: | 301.25 |
| Formula: | C14H11N3O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
ALE-0540, a nonpeptidic small molecule, is a nerve growth factor receptor antagonist. ALE-0540 inhibits the binding of NGF to tyrosine kinase (Trk) A or both p75 and TrkA with IC50 values of 5.88 μM and 3.72 μM, respectively. ALE-0540 can be used to examine mechanisms leading to the development of agents for the treatment of pain[1]. IC50 & Target:IC50: 5.88 μM (the binding of NGF to tyrosine kinase (Trk) A and TrkA); 3.72 μM (the binding of NGF to p75 and TrkA)[1].
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