Propargyl-Tos


CAS No. : 23418-85-1

23418-85-1
Price and Availability of CAS No. : 23418-85-1
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Cat. No. : HY-79584
M.Wt: 224.28
Formula: C11H12O3S
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 23418-85-1 :

Propargyl-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-Tos is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

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