Nefopam (hydrochloride)


CAS No. : 23327-57-3

(Synonyms: Fenazoxine (hydrochloride))

23327-57-3
Price and Availability of CAS No. : 23327-57-3
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500mg $45 In-stock
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Cat. No. : HY-B1057
M.Wt: 289.80
Formula: C17H20ClNO
Purity: >98 %
Solubility: H2O : 12.5 mg/mL (ultrasonic);DMSO : 12.5 mg/mL (ultrasonic)
Introduction of 23327-57-3 :

Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo[1][2]. In Vitro: Nefopam hydrochloride (Fenazoxine hydrochloride) is a non-opioid, non-steroidal, centrally acting analgesic drug that is derivative of the non-sedative benzoxazocine[1]. Constitutively elevated β-catenin leads to a delayed and fibrous fracture repair process, and Nefopam inhibits β-catenin mediated signaling during skin wound repair3].

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