LG190178
CAS No. : 233268-81-0
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| Cat. No. : | HY-117182 |
| M.Wt: | 458.63 |
| Formula: | C28H42O5 |
| Purity: | >98 % |
| Solubility: |
LG190178 is a non-steroidal vitamin D receptor (VDR) ligand that can induce the formation of heterodimer complexes between VDR and retinoid X receptor (RXR), stabilizing the agonistic conformation of the VDR ligand-binding domain and promoting its interaction with co-activators. LG190178 has functions in regulating calcium homeostasis, bone mineralization, as well as cell proliferation, differentiation, and apoptosis, making it useful for research in psoriasis, osteoporosis, and cancer[1].
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