Ferulic acid methyl ester
CAS No. : 2309-07-1
(Synonyms: Methyl ferulate)
| Size | Price | Stock |
|---|---|---|
| 10g | $22 | In-stock |
| 25g | $36 | In-stock |
| 100g | $100 | In-stock |
| 500g | $338 | In-stock |
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| 2 kg | Get quote | |
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| Cat. No. : | HY-W018643 |
| M.Wt: | 208.21 |
| Formula: | C11H12O4 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL;H2O : 2 mg/mL (ultrasonic) |
Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties[1][2]. Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders[1]. Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages[2].
IC50 & Target: p38[2]
In Vitro: Ferulic acid methyl ester (25 µg/mL) has no cytotoxic effects on BMDMs after treatment for 6 h, 18 h, 48 h[2].
Ferulic acid methyl ester (Methyl ferulate; 5, 10, 25 µg/mL) suppresses TNFα, IL6, IFNγ but not IL10, inhibits NO generation at 10 and 25 µg/mL, in primary bone marrow derived-macrophages (BMDMs)[2].
Ferulic acid methyl ester (25 µg/mL) inhibits COX-2 expression, blocks p-p38 and p-JNK[2].
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