BMS-284640
CAS No. : 230640-88-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $1080 | In-stock |
| 10mg | $1800 | In-stock |
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| Cat. No. : | HY-120623 |
| M.Wt: | 273.33 |
| Formula: | C15H19N3O2 |
| Purity: | >98 % |
| Solubility: |
BMS-284640 is a synthetic sodium hydrogen exchange isomer-1 (NHE-1) inhibitor. BMS-284640 has a more than 380-fold higher NHE-1 inhibitory activity (IC50: 9 nM) compared to cariporide (HY-19693) and is more selective for NHE-1 over NHE-2 (IC50: 1.8 μM) and NHE-5 (IC50: 3.36 μM). BMS-284640 and its analogs also exhibit enhanced oral bioavailability and prolonged plasma half-life in rats.[1]. IC50 & Target:IC50: 9 nM (NHE-1), 1.8 μM (NHE-2)[1]
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