Sinensetin
CAS No. : 2306-27-6
(Synonyms: Pedalitin permethyl ether)
| Size | Price | Stock |
|---|---|---|
| 1mg | $34 | In-stock |
| 5mg | $72 | In-stock |
| 10mg | $120 | In-stock |
| 25mg | $264 | In-stock |
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| Cat. No. : | HY-N0297 |
| M.Wt: | 372.37 |
| Formula: | C20H20O7 |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C) |
Sinensetin is a methylated flavonoid found in fruits that has strong anti-vascular and anti-inflammatory properties.
In Vitro:Sinensetin (40 μM, 2 d) enhances adipogenesis of 3T3-L1 preadipocytes by up-regulating the adipogenic transcription factors in the absence of IBMX[1].
Sinensetin (12-200 μM, 24-48 h) shows significant cytotoxic effects on Jurkat and CCRF-CEM cells in a dose-dependent and time-dependent manner[4].
Sinensetin (100 μM, 48h) induces the sub-G1 phase and apoptosis in Jurkat cells[4].
In Vivo:Sinensetin (50 mg/kg, single dose, i.p.) has anti-inflammatory effects on carrageenan (HY-125474) induced paw inflammation in the mouse[5].
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