Benznidazole
CAS No. : 22994-85-0
(Synonyms: Benznidazol; Ro 07-1051; Ro 71051)
| Size | Price | Stock |
|---|---|---|
| 25mg | $40 | In-stock |
| 50mg | $60 | In-stock |
| 100mg | $80 | In-stock |
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| Cat. No. : | HY-B1548 |
| M.Wt: | 260.25 |
| Formula: | C12H12N4O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease[1][2]. In Vivo:Benznidazole (100 mg/kg/day, p.o., 30 days) produces a decrease in electrocardiographic alterations, fewer modifications in the affinity and density of cardiac-receptors, and few isolated areas of fibrosis in the heart, in mice infected with Trypanosoma cruzi Tulahuen strain or SGO-Z12 isolate and treated at 180 days post infection (p.i.) (i.e. chronic phase) with Benznidazole[1].
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