Contulakin G
CAS No. : 229180-41-0
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| Cat. No. : | HY-P0066 |
| M.Wt: | 2070.17 |
| Formula: | C88H140N20O37 |
| Purity: | >98 % |
| Solubility: | H2O |
Contulakin G is an O-glycosylated invertebrate neurotensin. Contulakin-G is a weaker agonist for the neurotensin receptor. Contulakin G is also a potent antinociceptive agent[1][2].
In Vivo:Contulakin G exhibits potent analgesic activity in three pain models in rats following intrathecal delivery, namely in tail-flick (acute pain), formalin test, and CFA-induced allodynia inflammatory pain[1].
Contulakin G (0-3 nmoL, Intrathecally) significantly decreases flinching behavior in rats[2].
Contulakin G (50-500 nmoL, Intrathecally) produces a dose-dependent increase in the thermally evoked skin twitch latency by 30 min after administration in dogs[2].
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