Ceftaroline fosamil (inner)
CAS No. : 229016-73-3
(Synonyms: TAK-599 (free acid); PPI0903 (free acid))
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| Cat. No. : | HY-14738 |
| M.Wt: | 684.68 |
| Formula: | C22H21N8O8PS4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Ceftaroline fosamil (inner) (TAK-599 free acid), a cephalosporin derivative, is an N-phosphono proagent of anti-methicillin-resistant Staphylococcus aureus (MRSA) T-91825. Ceftaroline fosamil (inner) can be used for the research of MRSA infection[1][2][3].
In Vivo:Ceftaroline fosamil inner salt (s.c.) shows protective effects against experimental systemic infection caused by S. aureus N133 in mice, with ED50s of 1.60-2.37 mg/kg[1].
Ceftaroline fosamil inner salt (10 mg/kg; s.c.) disappeares rapidly and converts smoothly into T-91825 in blood of rats and monkeys[1].
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