TZD18
CAS No. : 228577-00-2
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| Cat. No. : | HY-121798 |
| M.Wt: | 477.57 |
| Formula: | C27H27NO5S |
| Purity: | >98 % |
| Solubility: |
TZD18 is a potent and orally active PPARα and PPARγ dual agonist with IC50 values of 0.028, 0.057, >10 µM for PPARα, PPARγ, PPARδ, respectively. TZD18 reduces plasma levels of both glucose and triglycerides in diabetic mice. TZD18 has the potential for the research of type 2 diabetes[1]. In Vivo:TZD18 (3, 10 mg/kg; p.o.; daily for 11 days) completes the correction of elevated plasma levels of both glucose and triglycerides in diabetic mice[1].
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