Maralixibat (chloride)
CAS No. : 228113-66-4
(Synonyms: SHP625 (chloride); LUM001 (chloride); Lopixibat (chloride))
| Size | Price | Stock |
|---|---|---|
| 1mg | $320 | In-stock |
| 5mg | $600 | In-stock |
| 10mg | $900 | In-stock |
| 25mg | $1620 | In-stock |
| 50mg | $2268 | In-stock |
| 100mg | $3175 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-16747 |
| M.Wt: | 710.41 |
| Formula: | C40H56ClN3O4S |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C) |
Maralixibat (SHP625) chloride is an orally active ileal bile acid transporter (IBAT) inhibitor. Maralixibat chloride can be used for the treatment of rare cholestatic liver diseases including Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC) and biliary atresia[1][2]. In Vivo:Maralixibat chloride reduces elevations in sBA levels, improves liver function, and reduces liver tissue damage, in a rat partial bile duct ligation model of cholestasis[2].
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