MCT1-IN-2


CAS No. : 227321-12-2

227321-12-2
Price and Availability of CAS No. : 227321-12-2
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Cat. No. : HY-18974
M.Wt: 435.58
Formula: C25H29N3O2S
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 227321-12-2 :

MCT1-IN-2 is a potent monocarboxylate transporter 1 (MCT1) inhibitor. MCT1-IN-2 has anti-cancer activity[1][2]. In Vitro: MCT1-IN-2 (compound 3) has a pKi of 9.48 for Jurkat T-cells and inhibits human peripheral blood mononuclear cells (PBMC) proliferation (pIC50=8.61)[1].
MCT1-IN-2 (compound 1) has an EC50 of 5.5 nM (MTT assay) and an IC50 of 105 nM (lactate transport inhibition assay) in human Raji lymphoma cell proliferation[2].

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