(E)-2-Hexadecenal
CAS No. : 22644-96-8
(Synonyms: 16:1 Aldehyde; trans-2-Hexadecenal)
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| Cat. No. : | HY-121683 |
| M.Wt: | 238.41 |
| Formula: | C16H30O |
| Purity: | >98 % |
| Solubility: |
(E)-2-Hexadecenal (trans-2-Hexadecenal) is an MLK3 activator that induces cytoskeletal remodeling, leading to cell rounding, detachment, and ultimately apoptosis in human and mouse cells. (E)-2-Hexadecenal activates the MLK3 signaling pathway, phosphorylating MKK4/7 and JNK, subsequently activating downstream targets of JNK, such as c-Jun phosphorylation, cytochrome c release, Bax activation, Bid cleavage, and Bim translocation to mitochondria. (E)-2-Hexadecenal has potential applications in research related to sphingolipid signaling pathways[1].
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