Ilicicolin A
CAS No. : 22581-06-2
(Synonyms: LL-Z 1272-alpha)
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| Cat. No. : | HY-122108 |
| M.Wt: | 390.94 |
| Formula: | C23H31ClO3 |
| Purity: | >98 % |
| Solubility: |
Ilicicolin A is a potent anticancer agent. Ilicicolin A induces apoptosis. Ilicicolin A inhibits cell growth and colony formation. Ilicicolin A shows antitumor activity. Ilicicolin A has the potential for the research of prostate cancer[1].
In Vitro:Ilicicolin A (0, 2.5, 5, 10 µM; 48 h) induces apoptosis in 22Rv1, C4-2B cells[1].
Ilicicolin A (0, 2.5, 5, 10 µM) inhibits cell growth and colony formation in 22Rv1 cells and C4-2B cells in a dose-dependent manner[1].
Ilicicolin A (0, 2.5, 5, 10 µM; 48 h) decreases the protein expression of EZH2, AURKA, PLK1, FoxM1, Cyclin B2, AR, c-Myc, cyclin D1[1].
Ilicicolin A (0, 2.5, 5, 10 µM; 48 h) decreases the mRNA expression of AR, ALK2, ALK3 in a dose-dependent manner[1].
In Vivo:Ilicicolin A (10 mg/kg; i.p.; six times a week for 3 weeks) inhibits tumor growth in mice[1].
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