TH5427
CAS No. : 2253744-56-6
| Size | Price | Stock |
|---|---|---|
| 1mg | $200 | In-stock |
| 5mg | $450 | In-stock |
| 10mg | $650 | In-stock |
| 25mg | $1110 | In-stock |
| 50mg | $1450 | In-stock |
| 100mg | $1885 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-125209 |
| M.Wt: | 491.33 |
| Formula: | C20H20Cl2N8O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C) |
TH5427 is a promising, targeted inhibitor that can be used to further study NUDT5 activity and ADP-ribose metabolism. TH5427, blocks progestin-dependent, PAR-derived nuclear ATP synthesis and subsequent chromatin remodeling, gene regulation and proliferation in breast cancer cells. NUDT5 is recently identified as a rheostat of hormone-dependent gene regulation and proliferation in breast cancer cells[1].
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