PROTAC BTK Degrader-2


CAS No. : 2250382-66-0

2250382-66-0
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Cat. No. : HY-122828
M.Wt: 976.97
Formula: C47H54F2N8O13
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 2250382-66-0 :

PROTAC BTK Degrader-2 is a potent BTK PROTAC degrader. PROTAC BTK Degrader-2 effectively reduces BTK protein levels[1]. In Vitro: PROTAC BTK Degrader-2 (compound 10; 1 µM; 24 h; Ramos cells) facilitates BTK degradation in cultured cells[1]. In Vivo: PROTAC BTK Degrader-2 (compound 10; 0-175 mg/kg; s.c.) selectively degrades BTK in rats[1].

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