SB 235375
CAS No. : 224961-34-6
| Size | Price | Stock |
|---|---|---|
| 5mg | $610 | In-stock |
| 10mg | $1100 | In-stock |
| 25mg | $2000 | In-stock |
| 50mg | $3000 | In-stock |
| 100mg | $4200 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-117380 |
| M.Wt: | 440.49 |
| Formula: | C27H24N2O4 |
| Purity: | >98 % |
| Solubility: |
SB 235375 is a potent and selective antagonist of the human neurokinin-3 (hNK-3) receptor designed by optimizing the structure of 2-phenyl-4-quinolinecarboxylic acid amide. SB 235375 displays high affinity for the hNK-3 receptor, with significantly higher binding affinities than hNK-2 and hNK-1 receptors. In vitro studies demonstrated its ability to block NK-3 receptor-mediated contraction and calcium mobilization, while in vivo, SB 223412 demonstrated oral and intravenous activity against NK-3 receptor-driven responses in animal models[1].
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