Ubavitinib


CAS No. : 2248003-60-1

(Synonyms: AZD3229)

2248003-60-1
Price and Availability of CAS No. : 2248003-60-1
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5mg $185 In-stock
10mg $290 In-stock
25mg $530 In-stock
50mg $880 In-stock
100mg $1480 In-stock
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Cat. No. : HY-112802
M.Wt: 479.51
Formula: C24H26FN7O3
Purity: >98 %
Solubility: DMSO : 40 mg/mL (ultrasonic)
Introduction of 2248003-60-1 :

AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. AZD3229 inhibits c-KIT with an IC50 value of 223.3 nM[1][2]. IC50 & Target:IC50: 223.3 nM (c-Kit)[2] In Vitro: AZD3229 is a potent, pan-KIT mutant inhibitor with potent single digit nM growth inhibition against a diverse panel of mutant KIT driven Ba/F3 cell lines (GI50=1-50 nM)[1].

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