Benfotiamine
CAS No. : 22457-89-2
(Synonyms: S-Benzoylthiamine O-monophosphate)
| Size | Price | Stock |
|---|---|---|
| 500mg | $95 | In-stock |
| 1g | $162 | In-stock |
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| Cat. No. : | HY-17374 |
| M.Wt: | 466.45 |
| Formula: | C19H23N4O6PS |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 50 mg/mL;H2O : 0.67 mg/mL (ultrasonic) |
Benfotiamine (S-Benzoylthiamine O-monophosphate) is a vitamin B1 derivative that exhihibits potent antioxidative and anti-inflammatory activity. Benfotiamine can be used for the research of various secondary diabetic complications. Benfotiamine also can be used in infectious diseases such as HIV and COVID-19[1][2][3].
In Vitro:Benfotiamine (50-250 μM; pretreated for 30 min and then exposed to LPS for 24 h) decreases LPS-induced production of NO by suppressing iNOS-mRNA and protein level in BV-2 cells[2].
Benfotiamine (50-250 μM; pretreated for 30 min and then exposed to LPS for 6 h) suppresses LPS-induced PTGS mRNA expression and COX-2 protein expression in BV2 microglial cells[2].
In Vivo:Benfotiamine (100 mg/kg; i.p. for 14 d) alleviates STZ (HY-13753)-induced cerebral oxidative damage of FVB mice[3].
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