(S,R,S)-AHPC-C4-NH2 (hydrochloride)


CAS No. : 2245697-83-8

(Synonyms: VH032-C4-NH2 (hydrochloride); VHL Ligand-Linker Conjugates 13; E3 ligase Ligand-Linker Conjugates 28)

2245697-83-8
Price and Availability of CAS No. : 2245697-83-8
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100mg $550 In-stock
500mg $1950 In-stock
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2g $4900 In-stock
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Cat. No. : HY-114176
M.Wt: 566.16
Formula: C27H40ClN5O4S
Purity: >98 %
Solubility: DMSO : ≥ 109.6 mg/mL;H2O : ≥ 50 mg/mL
Introduction of 2245697-83-8 :

(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1]. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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