Alloxan (hydrate)


CAS No. : 2244-11-3

2244-11-3
Price and Availability of CAS No. : 2244-11-3
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Cat. No. : HY-W017227
M.Wt: 160.08
Formula: C4H4N2O5
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic);H2O : ≥ 100 mg/mL
Introduction of 2244-11-3 :

Alloxan hydrate is a diabetogenic agent to induce diabetes. Alloxan hydrate is a proteasome inhibitor. Alloxan causes diabetes in experimental animals through its ability to destroy the insulin-secreting B-cells of the pancreas[1][2]. In Vitro: Alloxan hydrate inhibits the peptidase activities of the purified 26S and 20S proteasomes[1].

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