SI-2


CAS No. : 223788-33-8

(Synonyms: EPH 116)

223788-33-8
Price and Availability of CAS No. : 223788-33-8
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Cat. No. : HY-101447
M.Wt: 265.31
Formula: C15H15N5
Purity: >98 %
Solubility:
Introduction of 223788-33-8 :

SI-2 (EPH 116) is an inhibitor for steroid receptor coactivator-3 (SRC-3), which reduces the transcriptional activity and protein concentration of SRC-3 in cells, exhibits cytotoxicity in cancer cell, inhibits migration of MDA-MB-468, induces apoptosis of MDA-MB-468. SI-2 inhibits the tumor growth in mouse models, without significant toxicity for heart and other major organs (20 mg/kg)[1].

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