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|---|---|---|
| 100 mg | Get quote | |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-111103A |
| M.Wt: | 448.35 |
| Formula: | C20H23Cl2N7O |
| Purity: | >98 % |
| Solubility: |
CZh226 hydrochloride is a potent and selective PAK4 inhibitor with an IC50 of 18 nM, and its selectivity for PAK1 is 346 times. The oral bioavailability of CZh226 hydrochloride is poor, and it requires the use of the prodrug PAK4-IN-1 (HY-130628) to improve absorption and metabolic stability. CZh226 hydrochloride can be used for research on colorectal cancer and melanoma[1].
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