Pegaptanib (sodium)
CAS No. : 222716-86-1
(Synonyms: EYE001; NX1838)
| Size | Price | Stock |
|---|---|---|
| 1mg | $194 | In-stock |
| 5mg | $484 | In-stock |
| 10mg | $722 | In-stock |
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| Cat. No. : | HY-109561 |
| M.Wt: | 1000.00 |
| Formula: | C294H342F13N107Na28O188P28[C2H4O]n |
| Purity: | >98 % |
| Solubility: | H2O : 10 mg/mL (ultrasonic) |
Pegaptanib sodium is an RNA aptamer with polyethylene glycol modifications, which is directed against vascular endothelial growth factor (VEGF)-165. Pegaptanib could be used for the study of neovascular age-related macular degeneration (AMD) [1]. In Vitro:Pegaptanib also inhibits VEGF165-mediated phosphorylation of VEGFR2 and phospholipase Cγ and inhibited VEGF165-induced calcium mobilization in human umbilical vein endothelial cells[1].
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