Dynarrestin
CAS No. : 2222768-84-3
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| 10mg | $187 | In-stock |
| 50mg | $495 | In-stock |
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| Cat. No. : | HY-121802 |
| M.Wt: | 431.50 |
| Formula: | C22H23F2N3O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 83.33 mg/mL (ultrasonic) |
Dynarrestin is a aminothiazole inhibitor of cytoplasmic dyneins 1 and 2. Dynarrestin rapidly and reversibly inhibits dynein 1-driven microtubule gliding in vitro plus a range of dynein 1- and 2-dependent processes in cells without affecting ATP hydrolysis and interfering with ciliogenesis. Dynarrestin suppresses hedgehog (Hh)-dependent proliferation of neuronal precursors and tumor cells[1].
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