RET-IN-1


CAS No. : 2222755-14-6

2222755-14-6
Price and Availability of CAS No. : 2222755-14-6
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Cat. No. : HY-112950
M.Wt: 553.61
Formula: C29H31N9O3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 2222755-14-6 :

RET-IN-1 is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 552, has IC50s of 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively [1]. IC50 & Target: IC50: 1 nM (RETWT), 7 nM (RETV804M), 101 nM (RETG810R)

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