LANA-IN-1


CAS No. : 2221-00-3

(Synonyms: 4-(1H-Imidazol-1-yl)aniline)

2221-00-3
Price and Availability of CAS No. : 2221-00-3
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Cat. No. : HY-W015462
M.Wt: 159.19
Formula: C9H9N3
Purity: >98 %
Solubility:
Introduction of 2221-00-3 :

LANA-IN-1 (compound 8) is an N-acetyl-derived LANA inhibitor with antiviral activity against herpesvirus. In fluorescence assays using the LANA probe LBS2, 1 mM LANA-IN-1 shows an inhibition rate of 32%. LANA-IN-1 may inhibit the interaction between LANA and the viral genome[1]. In Vitro:LANA (latency-associated nuclear antigen) is an essential protein for Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8 during latent replication and persistence. LANA functions by replicating the viral episome and tethering it to the host chromatin[1].

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