Pyrantel (pamoate)


CAS No. : 22204-24-6

(Synonyms: Pyrantel embonate)

22204-24-6
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Cat. No. : HY-12640
M.Wt: 594.68
Formula: C34H30N2O6S
Purity: >98 %
Solubility: DMSO : 20.83 mg/mL (ultrasonic;warming;heat to 70°C)
Introduction of 22204-24-6 :

Pyrantel pamoate (Pyrantel embonate) is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel pamoate can cause spasmodic muscle paralysis in parasites. Pyrantel pamoate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis[1][2]. IC50 & Target:Parasites[1][2]. In Vitro:Pyrantel pamoate (10 nM-10 µM; 72 h) shows good anti-A. suum and (0-168.2 M; 72 h) anti-N. americanus activity[1][2]. In Vivo:Pyrantel pamoate (10 mg/kg; p.o.; single) reduces the worms in A. ceylanicum-infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4%[2].

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