CDK12-IN-3
CAS No. : 2220184-50-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $330 | In-stock |
| 10mg | $540 | In-stock |
| 25mg | $1130 | In-stock |
| 50mg | $1890 | In-stock |
| 100mg | $2500 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-112261 |
| M.Wt: | 470.52 |
| Formula: | C23H28F2N8O |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
CDK12-IN-3 is a potent and selective CDK12 inhibitor with an IC50 of 491 nM in enzymatic assay. IC50 & Target: IC50: 491 nM (CDK12)[1] In Vitro: CDK12-IN-3 is a highly selective CDK12 inhibitor profiled across a panel of 352 kinases at 0.1 µM. CDK12-IN-3 shows potent inhibition of phosphorylation of Ser2 on the CTD repeat domain of RNA Pol II as well as growth inhibition of OV90 cells and acute cytotoxicity to THP1 cells[1].
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- Cat. No.:
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