VU6007477
CAS No. : 2220141-46-6
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| Cat. No. : | HY-123934 |
| M.Wt: | 430.50 |
| Formula: | C24H26N6O2 |
| Purity: | >98 % |
| Solubility: |
VU6007477 is a brain-penetrant, selective M1 positive allosteric modulator (PAM) with an EC50 value of 230 nM. VU6007477 is also a human P-glycoprotein (P-gp) substrate with moderate permeability. VU6007477 displays improved central nervous system (CNS) penetration over the hydroxylated congeners. VU6007477 a pyranyl amide derivative, which is promising for research of robust cholinergic seizure activity[1].
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