CP-288886
CAS No. : 221332-74-7
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| Cat. No. : | HY-105358 |
| M.Wt: | 637.07 |
| Formula: | C30H28ClF3N2O6S |
| Purity: | >98 % |
| Solubility: |
CP-288886 is a cysLT1 receptor antagonist with a Ki value of 0.004 μM. CP-288886 exhibits comparable activity to Zafirlukast (HY-17492) and Pranlukast (HY-B0290). CP-288886 inhibits calcium mobilization with an IC50 of 0.0005 μM in human U937 cells. CP-288886 has high oral bioavailability. CP-288886 possesses anti-asthmatic activity in a guinea pig asthma model and can be used for the research of diseases such as asthma[1].
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