Crobenetine (hydrochloride)
CAS No. : 221018-88-8
(Synonyms: BIII-890 (hydrochloride); BIII-890 CL)
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| Cat. No. : | HY-16923A |
| M.Wt: | 416.00 |
| Formula: | C25H34ClNO2 |
| Purity: | >98 % |
| Solubility: |
Crobenetine hydrochloride (BIII-890 hydrochloride) is the hydrochloride form of Crobenetine (HY-16923). Crobenetine hydrochloride is a selective inhibitor for Na+ channel. Crobenetine hydrochloride displaces 3HBTX from site 2 of the Na+ channel (IC50=49 nM) in rat brain synaptosomes, exhibits only low binding affinity for other receptors and ion channels. Crobenetine hydrochloride protects brain tissue from the deleterious effects of focal cerebral ischemia in rodents[1].
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