JH-VIII-49


CAS No. : 2209084-73-9

2209084-73-9
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Cat. No. : HY-125001
M.Wt: 428.65
Formula: C30H40N2
Purity: >98 %
Solubility:
Introduction of 2209084-73-9 :

JH-VIII-49 (compound 10) is a potent and selective CDK8 inhibitor (IC50=16 nM) with excellent biological activity. JH-VIII-49 promotes CDK8 inhibition through its steroid backbone design. JH-VIII-49 can be used in the synthesis of PROTAC as a target protein ligand of JH-XI-10-02 (HY-111518)[1][2].

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