Valategrast
CAS No. : 220847-86-9
(Synonyms: R-411 (free base))
| Size | Price | Stock |
|---|---|---|
| 5mg | $380 | In-stock |
| 10mg | $600 | In-stock |
| 25mg | $1150 | In-stock |
| 50mg | $1800 | In-stock |
| 100mg | $2950 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-14190 |
| M.Wt: | 604.95 |
| Formula: | C30H32Cl3N3O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 170 mg/mL (ultrasonic) |
Valategrast (R-411 free base) is a potent and orally active integrin α4β1 (VLA-4) and α4β7 dual antagonist. Valategrast has the potential for Chronic obstructive pulmonary disease (COPD) and asthma treatment[1][2]. IC50 & Target: Integrin α4β1; Integrin α4β7[2] In Vitro: Valategrast contains a common l-phenylalanine-N-aroyl motif where the carboxylic acid is responsible for binding to the metal ion in the metal-ion-dependent adhesion site (MIDAS)[2].
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