Histrelin (acetate)
CAS No. : 220810-26-4
| Size | Price | Stock |
|---|---|---|
| 1mg | $100 | In-stock |
| 5mg | $220 | In-stock |
| 10mg | $350 | In-stock |
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| Cat. No. : | HY-P0056A |
| M.Wt: | 1000.00 |
| Formula: | C66H86N18O12.xC2H4O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO;10 mM in DMSO |
Histrelin acetate, a GnRH analogue, is a GnRH Receptor agonist. Histrelin acetate increases serum luteinising hormone (LH), follicle stimulating hormone (FSH) and testosterone levels. Histrelin acetate can be used in the research of prostate cancer, endometriosis[1][2][5].
In Vitro: Histrelin (10-100 nM) acetate stimulates the release of vasopressin (VP) from from isolated rat hypothalamo-neurohypophysial explants[4].
Histrelin (100 nM) acetate stimulates oxytocin (OT) release from the rat hypothalamo-neurohypophysial system[5].
In Vivo: Histrelin (0.1 mg/kg, subcutaneous injection) acetate rescues the circulating LH concentrations in Csfmop/Csfmop mice[2].
Histrelin (10,30, or 100 μg /day, subcutaneous injection) acetate reduces the number of endometrial glands and atrophied the stroma in rabbits[3].
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